A new synthesis of alkyl (E)-(3-dimethylamino)acrylates

A highly stereoselective one-step method for the synthesis of alkyl (E)-(3-dimethylamino)acrylates from N,N-dimethylformamide and ketene acetals is reported.

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Veröffentlicht in:Tetrahedron letters 2011-11, Vol.52 (46), p.6080-6081
Hauptverfasser: Robertson, Jeffrey M., Jones, Ian W., Kayne, Kevin M., Contreras, Cristina G., Witter, Daniel J., Bates, Robert B., Hall, H.K.
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container_end_page 6081
container_issue 46
container_start_page 6080
container_title Tetrahedron letters
container_volume 52
creator Robertson, Jeffrey M.
Jones, Ian W.
Kayne, Kevin M.
Contreras, Cristina G.
Witter, Daniel J.
Bates, Robert B.
Hall, H.K.
description A highly stereoselective one-step method for the synthesis of alkyl (E)-(3-dimethylamino)acrylates from N,N-dimethylformamide and ketene acetals is reported.
doi_str_mv 10.1016/j.tetlet.2011.09.003
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source ScienceDirect Journals (5 years ago - present)
subjects Acetals
Acrylates
Aliphatic compounds
Chemistry
Dimethylformamide
Exact sciences and technology
Ketene acetals
Ketenes
New synthetic method
Organic chemistry
Preparations and properties
Synthesis (chemistry)
Tetrahedrons
Vilsmeier reagent
title A new synthesis of alkyl (E)-(3-dimethylamino)acrylates
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