The first example of 1,3-dipolar cycloaddition reactions of nitrones to vinylidenecyclopropanes

The first example of 1,3-dipolar cycloaddition reactions of nitrones to vinylidenecyclopropanes is described. The nitrones react with the C1′–C2′ double bond of vinylidenecyclopropanes to give the corresponding 4-cyclopropylidene-isoxazolidines in moderate yields.

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Veröffentlicht in:Tetrahedron letters 2011-11, Vol.52 (44), p.5777-5781
Hauptverfasser: Larina, Anna G., Stepakov, Alexander V., Boitsov, Vitaly M., Molchanov, Alexander P., Gurzhiy, Vladislav V., Starova, Galina L., Lykholay, Anna N.
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Sprache:eng
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Zusammenfassung:The first example of 1,3-dipolar cycloaddition reactions of nitrones to vinylidenecyclopropanes is described. The nitrones react with the C1′–C2′ double bond of vinylidenecyclopropanes to give the corresponding 4-cyclopropylidene-isoxazolidines in moderate yields.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2011.08.116