Solid-phase synthesis of N-substituted 3,4-dihydroquinazolinone derivatives

Solid-phase synthesis of N-substituted 3,4-dihydroquinazolinone derivatives

An efficient solid-phase synthetic approach for the synthesis of N-substituted 3, 4-dihydroquinazolinone derivatives has been developed. Four different 2-nitrobenzoic acids and three different 2-phenylacetyl chlorides were employed in the synthesis of this library. After purification, all products w...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Tetrahedron letters 2011-05, Vol.52 (21), p.2627-2628
Hauptverfasser: Liu, Zhang, Ou, Lili, Giulianotti, Marc A., Houghten, Richard A.
Format: Artikel
Sprache:eng
Schlagworte:
Chemistry
Chlorides
Derivatives
Exact sciences and technology
Heterocyclic compounds
Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings
Libraries
Organic chemistry
Preparations and properties
Purification
Synthesis (chemistry)
Tetrahedrons
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:An efficient solid-phase synthetic approach for the synthesis of N-substituted 3, 4-dihydroquinazolinone derivatives has been developed. Four different 2-nitrobenzoic acids and three different 2-phenylacetyl chlorides were employed in the synthesis of this library. After purification, all products were obtained in good yields.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2011.03.034