Highly stereoselective imidazolethiones mediated Friedel–Crafts alkylation of indole derivatives
The asymmetric Friedel–Crafts alkylation of indoles with α ,β-unsaturated aldehydes was promoted by the novel imidazolethiones to afford the corresponding adducts in moderate to excellent yields and high enantioselectivities under mild reaction conditions. The asymmetric Friedel–Crafts alkylation of...
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| Veröffentlicht in: | Tetrahedron letters 2012-01, Vol.53 (3), p.289-291 |
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| container_title | Tetrahedron letters |
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| creator | Liang, Xianrui Li, Shuangmin Su, Weike |
| description | The asymmetric Friedel–Crafts alkylation of indoles with α
,β-unsaturated aldehydes was promoted by the novel imidazolethiones to afford the corresponding adducts in moderate to excellent yields and high enantioselectivities under mild reaction conditions.
The asymmetric Friedel–Crafts alkylation of indoles with α
,β-unsaturated aldehydes was promoted by the novel imidazolethiones to afford the corresponding adducts in moderate to excellent yields and high enantioselectivities under mild reaction conditions. |
| doi_str_mv | 10.1016/j.tetlet.2011.11.007 |
| format | Article |
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,β-unsaturated aldehydes was promoted by the novel imidazolethiones to afford the corresponding adducts in moderate to excellent yields and high enantioselectivities under mild reaction conditions.
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,β-unsaturated aldehydes was promoted by the novel imidazolethiones to afford the corresponding adducts in moderate to excellent yields and high enantioselectivities under mild reaction conditions.
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,β-unsaturated aldehydes was promoted by the novel imidazolethiones to afford the corresponding adducts in moderate to excellent yields and high enantioselectivities under mild reaction conditions.</description><subject>Adducts</subject><subject>Aldehydes</subject><subject>Alkylation</subject><subject>Asymmetry</subject><subject>Chemistry</subject><subject>Derivatives</subject><subject>Exact sciences and technology</subject><subject>Heterocyclic compounds</subject><subject>Heterocyclic compounds with only one n hetero atom and condensed derivatives</subject><subject>Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings</subject><subject>Indoles</subject><subject>Organic chemistry</subject><subject>Preparations and properties</subject><subject>Tetrahedrons</subject><issn>0040-4039</issn><issn>1873-3581</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNp9kMFKAzEQhoMoWKtv4GEvgpetk-5uNnsRpFgrFLzoOaTJxKamuzVJC_XkO_iGPokpKx4NA7l8_z_MR8glhREFym5Wo4jRYRyNgdJRGoD6iAwor4u8qDg9JgOAEvISiuaUnIWwgvQYhwFZzOzr0u2zENFjF9ChinaHmV1bLT-6VLq0XYshW6O2MqLOpt6iRvf9-TXx0sSQSfe2dzImLOtMZludUplGb3fyUBXOyYmRLuDF7z8kL9P758ksnz89PE7u5rkqWBNzQ41GRTkzmklmFsALrpGrhQHNWQlVYRoOiteoS6M1bcaNKQuqEGVjwMhiSK773o3v3rcYoljboNA52WK3DYLWZcnqumFVQsseVb4LwaMRG2_X0u8FBXFQKlaiVyoOSkWapDTFrn43yKCkM162yoa_7LhKh3A6Ttxtz2E6d2fRi6Astiop9Mmv0J39f9EPCLiTCA</recordid><startdate>20120118</startdate><enddate>20120118</enddate><creator>Liang, Xianrui</creator><creator>Li, Shuangmin</creator><creator>Su, Weike</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>L7M</scope></search><sort><creationdate>20120118</creationdate><title>Highly stereoselective imidazolethiones mediated Friedel–Crafts alkylation of indole derivatives</title><author>Liang, Xianrui ; Li, Shuangmin ; Su, Weike</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c369t-f1fdec186fd6a6fb0838de8cbf0d864053f980c87ed4fdd1929f431ceea9f0fa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adducts</topic><topic>Aldehydes</topic><topic>Alkylation</topic><topic>Asymmetry</topic><topic>Chemistry</topic><topic>Derivatives</topic><topic>Exact sciences and technology</topic><topic>Heterocyclic compounds</topic><topic>Heterocyclic compounds with only one n hetero atom and condensed derivatives</topic><topic>Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings</topic><topic>Indoles</topic><topic>Organic chemistry</topic><topic>Preparations and properties</topic><topic>Tetrahedrons</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Liang, Xianrui</creatorcontrib><creatorcontrib>Li, Shuangmin</creatorcontrib><creatorcontrib>Su, Weike</creatorcontrib><collection>Pascal-Francis</collection><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Tetrahedron letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Liang, Xianrui</au><au>Li, Shuangmin</au><au>Su, Weike</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Highly stereoselective imidazolethiones mediated Friedel–Crafts alkylation of indole derivatives</atitle><jtitle>Tetrahedron letters</jtitle><date>2012-01-18</date><risdate>2012</risdate><volume>53</volume><issue>3</issue><spage>289</spage><epage>291</epage><pages>289-291</pages><issn>0040-4039</issn><eissn>1873-3581</eissn><coden>TELEAY</coden><abstract>The asymmetric Friedel–Crafts alkylation of indoles with α
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| language | eng |
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| subjects | Adducts Aldehydes Alkylation Asymmetry Chemistry Derivatives Exact sciences and technology Heterocyclic compounds Heterocyclic compounds with only one n hetero atom and condensed derivatives Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings Indoles Organic chemistry Preparations and properties Tetrahedrons |
| title | Highly stereoselective imidazolethiones mediated Friedel–Crafts alkylation of indole derivatives |
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