Reactions of 2-(trifluoromethyl)chromones with cyanoacetamides, ethyl cyanoacetate and diethyl malonate. Unexpected synthesis of benzo[ c]coumarin derivatives

While 2-(trifluoromethyl)chromones react with cyanoacetamides in the presence of sodium ethoxide to produce 6-(2-hydroxyaryl)-4-(trifluoromethyl)-2-oxo-1,2-dihydropyridine-3-carbonitriles, their reactions with ethyl cyanoacetate and diethyl malonate under the same conditions took an entirely differe...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Tetrahedron letters 2011-11, Vol.52 (47), p.6271-6274
Hauptverfasser:	Sosnovskikh, Vyacheslav Ya, Safrygin, Alexander V., Anufriev, Viktor A., Eltsov, Oleg S., Iaroshenko, Viktor O.
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Pyridones 6 H-Benzo[ c]chromen-6-one Active methylene compounds Chromones Derivatives Sodium Synthesis (chemistry) Tetrahedrons Trifluoromethylated heterocycles
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	While 2-(trifluoromethyl)chromones react with cyanoacetamides in the presence of sodium ethoxide to produce 6-(2-hydroxyaryl)-4-(trifluoromethyl)-2-oxo-1,2-dihydropyridine-3-carbonitriles, their reactions with ethyl cyanoacetate and diethyl malonate under the same conditions took an entirely different course and gave novel functionalized derivatives of 6 H-benzo[ c]chromen-6-one.
ISSN:	0040-4039 1873-3581
DOI:	10.1016/j.tetlet.2011.09.082