A displacement assay for the sensing of protein interactions using sugar–tetraphenylethene conjugates

A displacement assay for the sensing of protein interactions using sugar–tetraphenylethene conjugates

A displacement sensor array based on sugar-substituted tetraphenylethenes with the aggregation-induced emission feature for proteins to perform screening of protein–protein interactions is demonstrated.

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Bibliographische Detailangaben
Veröffentlicht in:Tetrahedron letters 2010-12, Vol.51 (48), p.6331-6333
Hauptverfasser: Shiraishi, Kentaro, Sanji, Takanobu, Tanaka, Masato
Format: Artikel
Sprache:eng
Schlagworte:
Aggregation-induced emission
Biosensor
Carbohydrate
Conjugate
Conjugates
Detection
Displacement
Emission
Fluorescence
Lectin
Protein
Proteins
Screening
Sensor arrays
Tetrahedrons
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Beschreibung
Zusammenfassung:A displacement sensor array based on sugar-substituted tetraphenylethenes with the aggregation-induced emission feature for proteins to perform screening of protein–protein interactions is demonstrated.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2010.09.112