An improved synthesis of 2-oxa-7-azaspiro[3,5]nonane and analogs as novel reagents in medicinal chemistry

A detailed synthesis of novel spirocyclic oxetane analogs is described for the first time.

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Bibliographische Detailangaben
Veröffentlicht in:	Tetrahedron letters 2011-06, Vol.52 (26), p.3266-3270
Hauptverfasser:	Xu, Ruo, Czarniecki, Michael, Man, Jos de, Pan, Jianping, Qiang, Li, Root, Yuriko, Ying, Shihong, Su, Jing, Sun, Xijun, Zhang, Yuping, Yu, Tao, Zhang, Yang, Hu, Tao, Chen, Shu-Hui
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Oxa-6-azaspiro[3,4]octane 2-Oxa-6-azaspiro[3,5]nonane 2-Oxa-7-azaspiro[3,5]nonane Analogs Chemistry Exact sciences and technology Heterocyclic compounds Heterocyclic compounds with n hetero atom and also o and/or s, se, te hetero atoms Heterocyclic compounds with o, s, se, te hetero atom and condensed derivatives Organic chemistry Preparations and properties Spirocyclic oxetane Synthesis (chemistry) Tetrahedrons
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Beschreibung
Zusammenfassung:	A detailed synthesis of novel spirocyclic oxetane analogs is described for the first time.
ISSN:	0040-4039 1873-3581
DOI:	10.1016/j.tetlet.2011.04.054