Metastasis and Oxidative Stress: Are Antioxidants a Metabolic Driver of Progression?

The role of reactive oxygen species (ROS) and antioxidants in cancer is controversial because of their context-dependent ability to promote or suppress tumorigenesis. Piskounova et al. (2015) now show that ROS limit distant metastasis: only cells with increased antioxidant capacity are able to succe...

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Veröffentlicht in:	Cell metabolism 2015-12, Vol.22 (6), p.956-958
Hauptverfasser:	Peiris-Pagès, Maria, Martinez-Outschoorn, Ubaldo E., Sotgia, Federica, Lisanti, Michael P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Female Humans Male Melanoma - metabolism Melanoma - pathology Neoplasm Metastasis - prevention & control Oxidative Stress
Online-Zugang:	Volltext
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