Diabetic ketoacidosis in an HIV patient : a new mechanism of HIV protease inhibitor-induced glucose intolerance

Several medications used in HIV care such as didanosine, pentamidine, corticosteroids, megastrol acetate, and protease inhibitors have been associated with hyperglycemia. We report a case of severe hyperglycemic decompensation and propose a possible mechanism.

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Veröffentlicht in:AIDS (London) 1999-10, Vol.13 (14), p.1987-1989
Hauptverfasser: KAN, V. L, NYLEN, E. S
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container_end_page 1989
container_issue 14
container_start_page 1987
container_title AIDS (London)
container_volume 13
creator KAN, V. L
NYLEN, E. S
description Several medications used in HIV care such as didanosine, pentamidine, corticosteroids, megastrol acetate, and protease inhibitors have been associated with hyperglycemia. We report a case of severe hyperglycemic decompensation and propose a possible mechanism.
doi_str_mv 10.1097/00002030-199910010-00029
format Article
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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Journals@Ovid Complete
subjects Biological and medical sciences
Diabetic Ketoacidosis - chemically induced
Drug Therapy, Combination
Drug toxicity and drugs side effects treatment
Glucose Intolerance - chemically induced
Glucose Intolerance - drug therapy
HIV Infections - complications
HIV Infections - drug therapy
HIV Protease Inhibitors - adverse effects
HIV Protease Inhibitors - therapeutic use
Human immunodeficiency virus
Human immunodeficiency virus 1
Humans
Indinavir - adverse effects
Indinavir - therapeutic use
Lamivudine - therapeutic use
Male
Medical sciences
megestrol acetate
Middle Aged
Miscellaneous (drug allergy, mutagens, teratogens...)
pentamidine
Pharmacology. Drug treatments
proteinase inhibitors
Reverse Transcriptase Inhibitors - therapeutic use
Stavudine - therapeutic use
title Diabetic ketoacidosis in an HIV patient : a new mechanism of HIV protease inhibitor-induced glucose intolerance
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