Risk of Infection Using Peripherally Inserted Central and Umbilical Catheters in Preterm Neonates

To compare the rates of catheter-associated bloodstream infection (CABSI) in preterm infants born at .05) despite lower rates of late onset sepsis in the group of infants who received only a UVC. There was no significant difference in the incidence of CABSI between very preterm neonates who received a PICC, UVC, or UVC followed by PICC as the primary mode of venous access after birth. A prospective randomized controlled trial is justified to further guide practice regarding primary venous access and reduction of infection.