Mitochondrial fission and fusion
Mitochondria are key cellular organelles responsible for many different functions. The molecular biology of mitochondria is continuously subject to comprehensive studies. However, detailed mechanisms of mitochondrial biogenesis are still unclear. Fusion and fission are among the most enigmatic proce...
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Veröffentlicht in: | Biochemistry (Moscow) 2015-11, Vol.80 (11), p.1457-1464 |
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creator | Patrushev, M. V. Mazunin, I. O. Vinogradova, E. N. Kamenski, P. A. |
description | Mitochondria are key cellular organelles responsible for many different functions. The molecular biology of mitochondria is continuously subject to comprehensive studies. However, detailed mechanisms of mitochondrial biogenesis are still unclear. Fusion and fission are among the most enigmatic processes connected with mitochondria. On the other hand, it has been shown that these events are of great biological importance for functioning of living cells. In this review, we summarize existing molecular data on mitochondrial dynamics and discuss possible biological functions of fusion and fission of these organelles. |
doi_str_mv | 10.1134/S0006297915110061 |
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V. ; Mazunin, I. O. ; Vinogradova, E. N. ; Kamenski, P. A.</creator><creatorcontrib>Patrushev, M. V. ; Mazunin, I. O. ; Vinogradova, E. N. ; Kamenski, P. A.</creatorcontrib><description>Mitochondria are key cellular organelles responsible for many different functions. The molecular biology of mitochondria is continuously subject to comprehensive studies. However, detailed mechanisms of mitochondrial biogenesis are still unclear. Fusion and fission are among the most enigmatic processes connected with mitochondria. On the other hand, it has been shown that these events are of great biological importance for functioning of living cells. In this review, we summarize existing molecular data on mitochondrial dynamics and discuss possible biological functions of fusion and fission of these organelles.</description><identifier>ISSN: 0006-2979</identifier><identifier>EISSN: 1608-3040</identifier><identifier>DOI: 10.1134/S0006297915110061</identifier><identifier>PMID: 26615436</identifier><language>eng</language><publisher>Moscow: Pleiades Publishing</publisher><subject>Animals ; Biochemistry ; Biomedical and Life Sciences ; Biomedicine ; Bioorganic Chemistry ; Biosynthesis ; GTP Phosphohydrolases - genetics ; GTP Phosphohydrolases - metabolism ; Life Sciences ; Microbiology ; Mitochondria ; Mitochondria - metabolism ; Mitochondrial DNA ; Mitochondrial Dynamics - physiology ; Mitochondrial Proteins - genetics ; Mitochondrial Proteins - metabolism ; Molecular biology ; Observations ; Physiological aspects ; Review</subject><ispartof>Biochemistry (Moscow), 2015-11, Vol.80 (11), p.1457-1464</ispartof><rights>Pleiades Publishing, Ltd. 2015</rights><rights>COPYRIGHT 2015 Springer</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c400t-1ebdf80ba674b159a05030d61b2477c80ad950687590acf49d01d6b297fb92333</citedby><cites>FETCH-LOGICAL-c400t-1ebdf80ba674b159a05030d61b2477c80ad950687590acf49d01d6b297fb92333</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1134/S0006297915110061$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1134/S0006297915110061$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26615436$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Patrushev, M. 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subjects | Animals Biochemistry Biomedical and Life Sciences Biomedicine Bioorganic Chemistry Biosynthesis GTP Phosphohydrolases - genetics GTP Phosphohydrolases - metabolism Life Sciences Microbiology Mitochondria Mitochondria - metabolism Mitochondrial DNA Mitochondrial Dynamics - physiology Mitochondrial Proteins - genetics Mitochondrial Proteins - metabolism Molecular biology Observations Physiological aspects Review |
title | Mitochondrial fission and fusion |
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