Mitochondrial fission and fusion

Mitochondria are key cellular organelles responsible for many different functions. The molecular biology of mitochondria is continuously subject to comprehensive studies. However, detailed mechanisms of mitochondrial biogenesis are still unclear. Fusion and fission are among the most enigmatic proce...

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Veröffentlicht in:Biochemistry (Moscow) 2015-11, Vol.80 (11), p.1457-1464
Hauptverfasser: Patrushev, M. V., Mazunin, I. O., Vinogradova, E. N., Kamenski, P. A.
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container_issue 11
container_start_page 1457
container_title Biochemistry (Moscow)
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creator Patrushev, M. V.
Mazunin, I. O.
Vinogradova, E. N.
Kamenski, P. A.
description Mitochondria are key cellular organelles responsible for many different functions. The molecular biology of mitochondria is continuously subject to comprehensive studies. However, detailed mechanisms of mitochondrial biogenesis are still unclear. Fusion and fission are among the most enigmatic processes connected with mitochondria. On the other hand, it has been shown that these events are of great biological importance for functioning of living cells. In this review, we summarize existing molecular data on mitochondrial dynamics and discuss possible biological functions of fusion and fission of these organelles.
doi_str_mv 10.1134/S0006297915110061
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source MEDLINE; Springer Nature - Complete Springer Journals
subjects Animals
Biochemistry
Biomedical and Life Sciences
Biomedicine
Bioorganic Chemistry
Biosynthesis
GTP Phosphohydrolases - genetics
GTP Phosphohydrolases - metabolism
Life Sciences
Microbiology
Mitochondria
Mitochondria - metabolism
Mitochondrial DNA
Mitochondrial Dynamics - physiology
Mitochondrial Proteins - genetics
Mitochondrial Proteins - metabolism
Molecular biology
Observations
Physiological aspects
Review
title Mitochondrial fission and fusion
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