Mitochondrial fission and fusion

Mitochondria are key cellular organelles responsible for many different functions. The molecular biology of mitochondria is continuously subject to comprehensive studies. However, detailed mechanisms of mitochondrial biogenesis are still unclear. Fusion and fission are among the most enigmatic proce...

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Veröffentlicht in:Biochemistry (Moscow) 2015-11, Vol.80 (11), p.1457-1464
Hauptverfasser: Patrushev, M. V., Mazunin, I. O., Vinogradova, E. N., Kamenski, P. A.
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Sprache:eng
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Zusammenfassung:Mitochondria are key cellular organelles responsible for many different functions. The molecular biology of mitochondria is continuously subject to comprehensive studies. However, detailed mechanisms of mitochondrial biogenesis are still unclear. Fusion and fission are among the most enigmatic processes connected with mitochondria. On the other hand, it has been shown that these events are of great biological importance for functioning of living cells. In this review, we summarize existing molecular data on mitochondrial dynamics and discuss possible biological functions of fusion and fission of these organelles.
ISSN:0006-2979
1608-3040
DOI:10.1134/S0006297915110061