High intensity interval exercise decreases IL-8 and enhances the immunomodulatory cytokine interleukin-10 in lean and overweight–obese individuals

•Obese individuals exhibit a low grade systemic inflammatory profile.•High intensity interval exercise (HIIE) decreased IL-8 levels in lean and obese.•HIIE increased systemic levels of IL-6 and IL-10 in lean and obese.•HIIE may help reduce low grade inflammation in obesity.•Moderate exercise had no...

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Veröffentlicht in:	Cytokine (Philadelphia, Pa.) Pa.), 2016-01, Vol.77, p.1-9
Hauptverfasser:	Dorneles, Gilson P., Haddad, Desirée O., Fagundes, Viviane O., Vargas, Bruna K., Kloecker, Alana, Romão, Pedro R.T., Peres, Alessandra
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Body Mass Index Chemokine CCL2 - blood Creatine Kinase - blood Cytokine Enzyme-Linked Immunosorbent Assay Exercise - physiology Humans Inflammation Inflammation Mediators - blood Interleukin 1 Receptor Antagonist Protein - blood Interleukin-10 - blood Interleukin-17 - blood Interleukin-6 - blood Interleukin-8 - blood Interval exercise L-Lactate Dehydrogenase - blood Leukocyte Count Leukocytes Male Obesity Obesity - blood Overweight - blood Physical exercise Time Factors Young Adult
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Zusammenfassung:	•Obese individuals exhibit a low grade systemic inflammatory profile.•High intensity interval exercise (HIIE) decreased IL-8 levels in lean and obese.•HIIE increased systemic levels of IL-6 and IL-10 in lean and obese.•HIIE may help reduce low grade inflammation in obesity.•Moderate exercise had no effects in acute cytokine response in both groups. To compare the effects of two interval exercises with different intensities on acute inflammatory response in lean and overweight–obese subjects. Ten lean (BMI
ISSN:	1043-4666 1096-0023
DOI:	10.1016/j.cyto.2015.10.003