Differentiation of metastases from high-grade gliomas using short echo time super(1)H spectroscopy

Differentiation of metastases from high-grade gliomas using short echo time super(1)H spectroscopy

Purpose To determine if short echo time (TE) super(1)H magnetic resonance spectroscopy (MRS) can distinguish between intracranial metastases and glioblastomas. Materials and Methods TE 30-msec spectra were acquired (1.5 T) from voxels entirely within tumors from 23 glioblastoma patients and 24 metas...

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Veröffentlicht in:Journal of magnetic resonance imaging 2004-08, Vol.20 (2), p.187-192
Hauptverfasser: Opstad, K S, Murphy, M M, Wilkins, PR, Bell, BA, Griffiths, J R, Howe, F A
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Sprache:eng
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Zusammenfassung:Purpose To determine if short echo time (TE) super(1)H magnetic resonance spectroscopy (MRS) can distinguish between intracranial metastases and glioblastomas. Materials and Methods TE 30-msec spectra were acquired (1.5 T) from voxels entirely within tumors from 23 glioblastoma patients and 24 metastases patients (3 breast carcinomas, 1 bladder carcinoma, 8 lung carcinomas, 3 probable lung carcinomas, 6 melanomas, 1 stomach carcinoma, and 2 undetermined). Spectra were analyzed quantitatively (LCModel) to determine metabolite, lipid, and macromolecule concentrations. All tumors were previously untreated and classified histopathologically.
ISSN:1053-1807