Antifungal activity of some B, D-seco limonoids from two meliaceous plants

Isolation and characterization of B,D-seco limonoids from Swietenia mahogani have been described. Seven limonoids from S. mahogani and five limonoids from Khaya senegalensis were tested for antifungal activity against the groundnut rust Puccinia arachidis. Mexicanolide, 3β-acetoxy-mexicanolide, 3β-h...

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Veröffentlicht in:Journal of chemical ecology 1999-04, Vol.25 (4), p.923-933
Hauptverfasser: GOVINDACHARI, T. R, SURESH, G, BANUMATHY, B, MASILAMANI, S, GOPALAKRISHNAN, G, KRISHNA KUMARI, G. N
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Sprache:eng
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Zusammenfassung:Isolation and characterization of B,D-seco limonoids from Swietenia mahogani have been described. Seven limonoids from S. mahogani and five limonoids from Khaya senegalensis were tested for antifungal activity against the groundnut rust Puccinia arachidis. Mexicanolide, 3β-acetoxy-mexicanolide, 3β-hydroxymexicanolide, 2α,3β-dihydroxymexicanolide from K. senegalensis, and 6-acetylswietenine and 6-acetyl-3-tigloylswietenolide from S. mahogani effectively reduced the number of rust pustules on detached groundnut leaves. Possible correlation of structure to antifungal activity is discussed.[PUBLICATION ABSTRACT]
ISSN:0098-0331
1573-1561
DOI:10.1023/A:1020809204288