Timing of adjuvant chemotherapy and its relation to survival among patients with stage III colon cancer

Highlights • 14% of 6620 colon cancer patients started adjuvant chemotherapy >8 weeks. • Elderly patients were more likely to start chemotherapy >8 weeks post-surgery. • Various treatment factors were associated with starting chemotherapy >8 weeks. • Starting adjuvant chemotherapy >8 wee...

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Veröffentlicht in:	European journal of cancer (1990) 2015-11, Vol.51 (17), p.2553-2561
Hauptverfasser:	Bos, A.C.R.K, van Erning, F.N, van Gestel, Y.R.B.M, Creemers, G.J.M, Punt, C.J.A, van Oijen, M.G.H, Lemmens, V.E.P.P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvant chemotherapy Aged Chemotherapy, Adjuvant Colon - drug effects Colon - pathology Colon - surgery Colon cancer Colonic Neoplasms - drug therapy Colonic Neoplasms - pathology Colonic Neoplasms - surgery Combined Modality Therapy Delays in chemotherapy Female Hematology, Oncology and Palliative Medicine Humans Kaplan-Meier Estimate Logistic Models Lymphatic Metastasis Male Middle Aged Multivariate Analysis Neoplasm Staging Netherlands Outcome Assessment (Health Care) - methods Outcome Assessment (Health Care) - statistics & numerical data Postoperative Period Proportional Hazards Models Registries - statistics & numerical data Survival Time Factors Timing
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Zusammenfassung:	Highlights • 14% of 6620 colon cancer patients started adjuvant chemotherapy >8 weeks. • Elderly patients were more likely to start chemotherapy >8 weeks post-surgery. • Various treatment factors were associated with starting chemotherapy >8 weeks. • Starting adjuvant chemotherapy >8 weeks was associated with decreased survival. • Starting adjuvant chemotherapy 5–8 versus
ISSN:	0959-8049 1879-0852
DOI:	10.1016/j.ejca.2015.08.016