Nationwide population-based surveillance of invasive pneumococcal disease in Japanese children: Effects of the seven-valent pneumococcal conjugate vaccine

Highlights • A population-based surveillance of pediatric IPD provided the effectiveness of PCV7. • A 98% decline in the incidence of PCV7-type IPD was found after PCV7 introduction. • An absolute increase was found in the incidence of PCV13 minus PCV7-type IPD. • An increase of the rate of meropene...

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Veröffentlicht in:Vaccine 2015-11, Vol.33 (45), p.6054-6060
Hauptverfasser: Suga, Shigeru, Chang, Bin, Asada, Kazutoyo, Akeda, Hideki, Nishi, Junichiro, Okada, Kenji, Wakiguchi, Hiroshi, Maeda, Akihiko, Oda, Megumi, Ishiwada, Naruhiko, Saitoh, Akihiko, Oishi, Tomohiro, Hosoya, Mitsuaki, Togashi, Takehiro, Oishi, Kazunori, Ihara, Toshiaki
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container_end_page 6060
container_issue 45
container_start_page 6054
container_title Vaccine
container_volume 33
creator Suga, Shigeru
Chang, Bin
Asada, Kazutoyo
Akeda, Hideki
Nishi, Junichiro
Okada, Kenji
Wakiguchi, Hiroshi
Maeda, Akihiko
Oda, Megumi
Ishiwada, Naruhiko
Saitoh, Akihiko
Oishi, Tomohiro
Hosoya, Mitsuaki
Togashi, Takehiro
Oishi, Kazunori
Ihara, Toshiaki
description Highlights • A population-based surveillance of pediatric IPD provided the effectiveness of PCV7. • A 98% decline in the incidence of PCV7-type IPD was found after PCV7 introduction. • An absolute increase was found in the incidence of PCV13 minus PCV7-type IPD. • An increase of the rate of meropenem-nonsusceptible strains was found.
doi_str_mv 10.1016/j.vaccine.2015.07.069
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subjects Adolescent
Allergy and Immunology
Anti-Bacterial Agents - pharmacology
Child
Child, Preschool
Children
Drug Resistance, Multiple, Bacterial
Female
Heptavalent Pneumococcal Conjugate Vaccine - immunology
Humans
Immunization
Infant
Invasive pneumococcal disease
Japan
Japan - epidemiology
Male
Meningitis
Meropenem
Microbial Sensitivity Tests
Pneumococcal Infections - ethnology
Pneumococcal Infections - microbiology
Pneumococcal Infections - mortality
Pneumococcal Infections - prevention & control
Pneumonia
Population Surveillance
Prospective Studies
Serogroup
Serotype replacement
Seven-valent pneumococcal conjugate vaccine
Streptococcus pneumoniae
Streptococcus pneumoniae - classification
Streptococcus pneumoniae - drug effects
Streptococcus pneumoniae - pathogenicity
Thienamycins - pharmacology
Vaccines
title Nationwide population-based surveillance of invasive pneumococcal disease in Japanese children: Effects of the seven-valent pneumococcal conjugate vaccine
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