Nationwide population-based surveillance of invasive pneumococcal disease in Japanese children: Effects of the seven-valent pneumococcal conjugate vaccine

Nationwide population-based surveillance of invasive pneumococcal disease in Japanese children: Effects of the seven-valent pneumococcal conjugate vaccine

Highlights • A population-based surveillance of pediatric IPD provided the effectiveness of PCV7. • A 98% decline in the incidence of PCV7-type IPD was found after PCV7 introduction. • An absolute increase was found in the incidence of PCV13 minus PCV7-type IPD. • An increase of the rate of meropene...

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Veröffentlicht in:Vaccine 2015-11, Vol.33 (45), p.6054-6060
Hauptverfasser: Suga, Shigeru, Chang, Bin, Asada, Kazutoyo, Akeda, Hideki, Nishi, Junichiro, Okada, Kenji, Wakiguchi, Hiroshi, Maeda, Akihiko, Oda, Megumi, Ishiwada, Naruhiko, Saitoh, Akihiko, Oishi, Tomohiro, Hosoya, Mitsuaki, Togashi, Takehiro, Oishi, Kazunori, Ihara, Toshiaki
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Allergy and Immunology
Anti-Bacterial Agents - pharmacology
Child
Child, Preschool
Children
Drug Resistance, Multiple, Bacterial
Female
Heptavalent Pneumococcal Conjugate Vaccine - immunology
Humans
Immunization
Infant
Invasive pneumococcal disease
Japan
Japan - epidemiology
Male
Meningitis
Meropenem
Microbial Sensitivity Tests
Pneumococcal Infections - ethnology
Pneumococcal Infections - microbiology
Pneumococcal Infections - mortality
Pneumococcal Infections - prevention & control
Pneumonia
Population Surveillance
Prospective Studies
Serogroup
Serotype replacement
Seven-valent pneumococcal conjugate vaccine
Streptococcus pneumoniae
Streptococcus pneumoniae - classification
Streptococcus pneumoniae - drug effects
Streptococcus pneumoniae - pathogenicity
Thienamycins - pharmacology
Vaccines
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Zusammenfassung:Highlights • A population-based surveillance of pediatric IPD provided the effectiveness of PCV7. • A 98% decline in the incidence of PCV7-type IPD was found after PCV7 introduction. • An absolute increase was found in the incidence of PCV13 minus PCV7-type IPD. • An increase of the rate of meropenem-nonsusceptible strains was found.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2015.07.069