The risk of sensitization to furry animals in patients already sensitized to cat/dog: An in vitro evaluation using molecular-based allergy diagnostics

The risk of sensitization to furry animals in patients already sensitized to cat/dog: An in vitro evaluation using molecular-based allergy diagnostics

Present in vitro and previous in vivo4 data suggest that allergic sensitization to c/d increases the risk of sensitization to horse and mouse because of the presence of lipocalins. Because lipocalins show a certain degree of cross-reactivity,5 a similar finding for other furry animals is likely.

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Bibliographische Detailangaben
Veröffentlicht in:Journal of allergy and clinical immunology 2015-06, Vol.135 (6), p.1664-1666
Hauptverfasser: Liccardi, Gennaro, MD, Meriggi, Antonio, MD, Russo, Maria, PhD, Croce, Stefania, MS, Salzillo, Antonello, MD, Pignatti, Patrizia, PhD
Format: Artikel
Sprache:eng
Schlagworte:
Allergens - immunology
Allergies
Allergy and Immunology
Animals
Asthma - diagnosis
Hair - immunology
Humans
Hypersensitivity - diagnosis
Mammals
Pets
Rhinitis, Allergic, Perennial - diagnosis
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Beschreibung
Zusammenfassung:Present in vitro and previous in vivo4 data suggest that allergic sensitization to c/d increases the risk of sensitization to horse and mouse because of the presence of lipocalins. Because lipocalins show a certain degree of cross-reactivity,5 a similar finding for other furry animals is likely.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2015.03.021