Synthesis of Functionalized Chromeno­[2,3‑b]­pyrrol-4(1H)‑ones by Silver-Catalyzed Cascade Reactions of Chromones/Thiochromones and Isocyanoacetates

A novel and convenient approach to the synthesis of chromeno­[2,3-b]­pyrrol-4­(1H)-ones has been developed. Furthermore, the method involves a facile silver-catalyzed cascade cyclization reaction including an intramolecular C–O bond formation. The silver salt acts as a key promoter.

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Veröffentlicht in:Organic letters 2015-11, Vol.17 (22), p.5590-5593
Hauptverfasser: Qi, Xueyu, Xiang, Haoyue, Yang, Chunhao
Format: Artikel
Sprache:eng
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Zusammenfassung:A novel and convenient approach to the synthesis of chromeno­[2,3-b]­pyrrol-4­(1H)-ones has been developed. Furthermore, the method involves a facile silver-catalyzed cascade cyclization reaction including an intramolecular C–O bond formation. The silver salt acts as a key promoter.
ISSN:1523-7060
1523-7052
DOI:10.1021/acs.orglett.5b02795