Systems Neuroscience: Shaping the Reward Prediction Error Signal

A recent study shows that midbrain GABA (inhibitory) neurons code for environmentally predicted rewards. These GABA neurons communicate with dopamine neurons, where the reward prediction is subtracted from delivered reward. Thus, the GABA prediction signal shapes the dopamine reward prediction error signal. A recent study shows that midbrain GABA (inhibitory) neurons code for environmentally predicted rewards. These GABA neurons communicate with dopamine neurons, where the reward prediction is subtracted from delivered reward. Thus, the GABA prediction signal shapes the dopamine reward prediction error signal.