The evolution of Class II Aminoacyl-tRNA synthetases and the first code

•A new evolutionary sequence for the catalytic domain of the Class II synthetases.•Two alternate catalytic domain extensions leads to a split of the Class II synthetases associated with the operational code.•The earliest Class II synthetase may form the link between a Thioester world and a Phosphoes...

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Veröffentlicht in:	FEBS letters 2015-11, Vol.589 (23), p.3499-3507
Hauptverfasser:	Smith, Temple F., Hartman, Hyman
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acyl-tRNA Synthetases - chemistry Amino Acyl-tRNA Synthetases - metabolism Aminoacyl-tRNA-synthetase Catalytic Domain Evolution Evolution, Molecular Models, Molecular Operational-code Thioester
Online-Zugang:	Volltext
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