The Fatty Acid-binding Protein, aP2, Coordinates Macrophage Cholesterol Trafficking and Inflammatory Activity: Macrophage expression of aP2 affects peroxisome proloferator-activated receptor gamma and I Kappa B kinase activities

Fatty acid-binding proteins are cytosolic fatty acid chaperones, and the adipocyte isoform, aP2, plays an important role in obesity and glucose metabolism. Recently, this protein has been detected in macrophages where it strongly contributes to the development of atherosclerosis. Here, we investigat...

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Veröffentlicht in:	The Journal of biological chemistry 2005-04, Vol.280 (13), p.12888-12895
Hauptverfasser:	Makowski, Liza, Brittingham, Katherine C, Reynolds, Joseph M, Suttles, Jill, Hotamisligil, Goekhan S
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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