Increasing morbidity from myocardial infarction during HIV protease inhibitor treatment?

We have recently observed five cases of myocardial infarction (MI) within 6 months in one HIV outpatient department. All patients had been on protease inhibitor (PI) treatment for a median of 10 months. As lipid abnormalities and single cases of MI have been reported in patients treated with these d...

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Veröffentlicht in:	AIDS (London) 1999-09, Vol.13 (13), p.1796-1797
Hauptverfasser:	JÜTTE, A, SCHWENK, A, FRANZEN, C, RÖMER, K, DIET, F, DIEHL, V, FÄTKENHEUER, G, SALZBERGER, B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Drug toxicity and drugs side effects treatment HIV Infections - drug therapy HIV Protease Inhibitors - adverse effects HIV Protease Inhibitors - therapeutic use Human immunodeficiency virus Humans Male Medical sciences Middle Aged Myocardial Infarction - chemically induced Pharmacology. Drug treatments Toxicity: cardiovascular system
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Zusammenfassung:	We have recently observed five cases of myocardial infarction (MI) within 6 months in one HIV outpatient department. All patients had been on protease inhibitor (PI) treatment for a median of 10 months. As lipid abnormalities and single cases of MI have been reported in patients treated with these drugs, we examined retrospectively the incidence of MI in HIV patients depending on PI treatment.
ISSN:	0269-9370 1473-5571
DOI:	10.1097/00002030-199909100-00034