Endophilin-1 regulates blood-brain barrier permeability via EGFR-JNK signaling pathway

Abstract Endophilin-1 (Endo1), a multifunctional protein, is essential for synaptic vesicle endocytosis. However, the role and mechanism of endophilin-1 in blood–brain barrier (BBB) function are still unclear. This study was performed to determine whether endophilin-1 regulated BBB permeability via...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Brain research 2015-05, Vol.1606, p.44-53
Hauptverfasser:	Chen, Lin, Liu, Wenjing, Wang, Ping, Xue, Yixue, Su, Qingjie, Zeng, Chaosheng, Shang, Xiuli
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - metabolism Blood-Brain Barrier - metabolism Blood-Brain Barrier - ultrastructure Blood–brain barrier c-Jun N-terminal kinase Cell Line Endophilin-1 Epidermal growth factor receptor Humans JNK Mitogen-Activated Protein Kinases - metabolism MAP Kinase Signaling System Neurology Occludin - metabolism Permeability Phosphorylation Receptor, Epidermal Growth Factor - metabolism Tight junction Tight Junctions - ultrastructure Zonula Occludens-1 Protein - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!