Kaposi's Sarcoma in a Patient with Eosinophilic Granulomatosis with Polyangiitis While Taking Mycophenolate Mofetil

Human Herpesvirus-8 (HHV-8) DNA was detected in both peripheral blood (770 copies/mL) and histological samples (157,400 copies/mL), confirming the diagnosis. Because antibody testing might result negative given the immunosuppression, HIV was assessed by polymerase chain reaction and was negative. Maintenance therapy with azathioprine or methotrexate is needed to avoid relapses.1 Second-line treatment with MMF is considered in refractory disease or for those patients who have contraindications or experienced side effects with the first-line treatment.2-5 We reported here a patient affected by EPGA who developed KS while on MMF treatment.