PD-L1/PD-1 presence in the tumor microenvironment and activity of PD-1 blockade in multiple myeloma

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Veröffentlicht in:	Leukemia 2015-10, Vol.29 (10), p.2110-2113
Hauptverfasser:	Paiva, B, Azpilikueta, A, Puig, N, Ocio, E M, Sharma, R, Oyajobi, B O, Labiano, S, San-Segundo, L, Rodriguez, A, Aires-Mejia, I, Rodriguez, I, Escalante, F, de Coca, A G, Barez, A, San Miguel, J F, Melero, I
Format:	Artikel
Sprache:	eng
Schlagworte:	13/31 631/67/1059/2325 631/67/1990/804 631/80/86 692/699/67/327 Animals Apoptosis B7-H1 Antigen - metabolism Bone Marrow - metabolism Cancer Research Case-Control Studies Cells, Cultured Critical Care Medicine Development and progression Drug therapy Female Follow-Up Studies Gene expression Genetic aspects Genotype Health aspects Hematology Humans Identification and classification Immunophenotyping Immunotherapy Intensive Internal Medicine Killer Cells, Natural - metabolism Killer Cells, Natural - pathology letter-to-the-editor Medicine Medicine & Public Health Membrane proteins Methods Mice Mice, Inbred C57BL Multiple myeloma Multiple Myeloma - metabolism Multiple Myeloma - mortality Multiple Myeloma - pathology Neoplasm Recurrence, Local - metabolism Neoplasm Recurrence, Local - mortality Neoplasm Recurrence, Local - pathology Neoplasm Staging Neoplasm, Residual - metabolism Neoplasm, Residual - mortality Neoplasm, Residual - pathology Oncology PD-1 protein PD-L1 protein Prognosis Programmed Cell Death 1 Receptor - antagonists & inhibitors Programmed Cell Death 1 Receptor - metabolism Prospective Studies Stem Cells - metabolism Stem Cells - pathology Survival Rate T-Lymphocytes - metabolism T-Lymphocytes - pathology Tumor Microenvironment
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ISSN:	0887-6924 1476-5551
DOI:	10.1038/leu.2015.79