Molecular epidemiology and molecular characterization of respiratory syncytial viruses at a tertiary care university hospital in Catalonia (Spain) during the 2013–2014 season

Molecular epidemiology and molecular characterization of respiratory syncytial viruses at a tertiary care university hospital in Catalonia (Spain) during the 2013–2014 season

Highlights • The genetic variability of recent circulating HRSV strains in Catalonia (Spain) is described. • Both HRSV groups co-circulated during the 2013–14 season, but HRSV-B was predominant. • Different phylogenetic subgroups within ON-1 (HRSV-A) and BA9 (HRSV-B) were distinguished. • A strain c...

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Veröffentlicht in:Journal of clinical virology 2015-05, Vol.66, p.27-32
Hauptverfasser: Gimferrer, Laura, Campins, Magda, Codina, María Gema, Martín, María del Carmen, Fuentes, Francisco, Esperalba, Juliana, Bruguera, Andreu, Vilca, Luz María, Armadans, Lluís, Pumarola, Tomàs, Antón, Andrés
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Aged, 80 and over
Allergy and Immunology
Child, Preschool
Epidemiology
Female
Genotype
Genotypes
Hospitals, University
HRSV
Human respiratory syncytial virus
Humans
Infant
Infectious Disease
Male
Molecular
Molecular Epidemiology
Molecular Sequence Data
Palivizumab
Phylogeny
Respiratory syncytial virus
Respiratory Syncytial Virus Infections - epidemiology
Respiratory Syncytial Virus Infections - virology
Respiratory Syncytial Virus, Human - classification
Respiratory Syncytial Virus, Human - genetics
Respiratory Syncytial Virus, Human - isolation & purification
RNA, Viral - genetics
Sequence Analysis, DNA
Sequence Homology
Spain - epidemiology
Surveillance
Tertiary Healthcare
Viral Envelope Proteins - genetics
Viral Fusion Proteins - genetics
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Zusammenfassung:Highlights • The genetic variability of recent circulating HRSV strains in Catalonia (Spain) is described. • Both HRSV groups co-circulated during the 2013–14 season, but HRSV-B was predominant. • Different phylogenetic subgroups within ON-1 (HRSV-A) and BA9 (HRSV-B) were distinguished. • A strain carrying a mutation related to Palivizumab resistance was found. • The present study highlights the importance of an active HRSV surveillance.
ISSN:1386-6532
1873-5967
DOI:10.1016/j.jcv.2015.02.018