Exploring the effect of vitamin C on sleep deprivation induced memory impairment

Highlights • Chronic sleep deprivation impairs both short- and long-term hippocampal memory. • Vitamin C prevents sleep deprivation induced short- and long-term memory impairments. • This is probably achieved through antagonizing oxidative stress in the hippocampus.

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Bibliographische Detailangaben
Veröffentlicht in:	Brain research bulletin 2015-04, Vol.113, p.41-47
Hauptverfasser:	Mhaidat, Nizar M, Alzoubi, Karem H, Khabour, Omar F, Tashtoush, Noor H, Banihani, Saleem A, Abdul-razzak, Khalid K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Ascorbic Acid - pharmacology Catalase - metabolism Hippocampus Hippocampus - drug effects Hippocampus - enzymology Hippocampus - metabolism Learning - drug effects Male Maze Memory Memory Disorders - etiology Memory Disorders - metabolism Memory Disorders - prevention & control Neurology Oxidative Stress - drug effects Random Allocation Rats Rats, Wistar Sleep deprivation Sleep Deprivation - complications Sleep Deprivation - drug therapy Sleep Deprivation - metabolism Superoxide Dismutase - metabolism Thiobarbituric Acid Reactive Substances - metabolism Vitamin C
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Beschreibung
Zusammenfassung:	Highlights • Chronic sleep deprivation impairs both short- and long-term hippocampal memory. • Vitamin C prevents sleep deprivation induced short- and long-term memory impairments. • This is probably achieved through antagonizing oxidative stress in the hippocampus.
ISSN:	0361-9230 1873-2747
DOI:	10.1016/j.brainresbull.2015.02.002