Increased risk of non-AIDS-related events in HIV subjects with persistent low CD4 counts despite cART in the CoRIS cohort

•We explored clinical complications of HIV subjects with persistent low CD4 despite virological suppression under cART.•The persistence of low CD4 despite long-term virological suppression do not imply an increased risk of AIDS-defining events.•We found a greater risk for non-AIDS-defining diseases,...

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Veröffentlicht in:	Antiviral research 2015-05, Vol.117, p.69-74
Hauptverfasser:	Pacheco, Y.M., Jarrin, I., Rosado, I., Campins, A.A., Berenguer, J., Iribarren, J.A., Rivero, M., Muñoz-Medina, L., Bernal-Morell, E., Gutiérrez, F., Leal, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged AIDS Antiretroviral Therapy, Highly Active Cardiovascular Diseases - complications Cardiovascular Diseases - epidemiology CD4 Lymphocyte Count Clinical complications Cohort Studies Female HIV Infections - complications HIV Infections - drug therapy HIV Infections - immunology HIV Infections - virology Human immunodeficiency virus Humans Immunodeficiency Low-CD4 restoration Male Middle Aged Mortality Neoplasms - complications Neoplasms - epidemiology Non-AIDS-defining events Non-AIDS-defining malignancies Prospective Studies Regression Analysis Risk Factors Spain - epidemiology Time Factors Viral Load Young Adult
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