Is the shape of the decline in risk following quitting smoking similar for squamous cell carcinoma and adenocarcinoma of the lung? A quantitative review using the negative exponential model

Is the shape of the decline in risk following quitting smoking similar for squamous cell carcinoma and adenocarcinoma of the lung? A quantitative review using the negative exponential model

•We compared rates of decline in excess risk after quitting smoking for two major lung cancer types.•Our estimations used 17 data sets for squamous cell carcinoma (SqC) and 19 for adenocarcinoma (AdC).•The years to halve the excess risk from continued smoking was 11.47 for SqC and 14.44 for AdC.•The...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Regulatory toxicology and pharmacology 2015-06, Vol.72 (1), p.49-57
Hauptverfasser: Fry, John S., Lee, Peter N., Forey, Barbara A., Coombs, Katharine J.
Format: Artikel
Sprache:eng
Schlagworte:
Adenocarcinoma - etiology
Carcinoma, Squamous Cell - etiology
Case-Control Studies
Cessation of smoking
Female
Half-Life
Histological type
Humans
Lung cancer
Lung Neoplasms - etiology
Male
Meta-analysis
Negative exponential model
Prospective Studies
Review
Risk
Smoking
Smoking - adverse effects
Smoking Cessation - methods
Statistical models
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:•We compared rates of decline in excess risk after quitting smoking for two major lung cancer types.•Our estimations used 17 data sets for squamous cell carcinoma (SqC) and 19 for adenocarcinoma (AdC).•The years to halve the excess risk from continued smoking was 11.47 for SqC and 14.44 for AdC.•The ratio of the half-life for AdC to SqC was estimated as 1.32 (95% CI 1.20–1.46, p
ISSN:0273-2300
1096-0295
DOI:10.1016/j.yrtph.2015.02.010