Germinal Center Quality Control: Death by Fas

Fas is a cell surface death receptor critical for immune regulation. In this issue of Immunity, Butt et al. (2015) show that Fas eliminates B cells that have become uncoupled from positive and negative selection in the germinal center. Fas is a cell surface death receptor critical for immune regulat...

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Veröffentlicht in:Immunity (Cambridge, Mass.) Mass.), 2015-05, Vol.42 (5), p.783-785
1. Verfasser: Allen, Christopher D.C.
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description Fas is a cell surface death receptor critical for immune regulation. In this issue of Immunity, Butt et al. (2015) show that Fas eliminates B cells that have become uncoupled from positive and negative selection in the germinal center. Fas is a cell surface death receptor critical for immune regulation. Butt et al. (2015) show that Fas eliminates B cells that have become uncoupled from positive and negative selection in the germinal center.
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source MEDLINE; Cell Press Free Archives; ScienceDirect Journals (5 years ago - present); EZB-FREE-00999 freely available EZB journals
subjects Animals
Antigens
Autoantibodies - immunology
B-Lymphocytes - cytology
fas Receptor - immunology
Germinal Center - cytology
Germinal Center - immunology
Humans
Immune system
Immunoglobulin E - immunology
Immunoglobulins
Mutation
title Germinal Center Quality Control: Death by Fas
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