Phenotyping juvenile myoclonic epilepsy. Praxis induction as a biomarker of unfavorable prognosis

Highlights • There is a male preponderance in juvenile myoclonic epilepsy patients with praxis induction. • Praxis induction is related to focal epileptiform discharges. • Praxis induction is related to loss of the characteristic chronodependency of juvenile myoclonic epilepsy and with reduced respo...

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Veröffentlicht in:	Seizure (London, England) England), 2015-11, Vol.32, p.62-68
Hauptverfasser:	Uchida, Carina Gonçalves Pedroso, de Carvalho, Kelly Cristina, Guaranha, Mirian Salvadori Bittar, Guilhoto, Laura Maria Figueiredo F, de Araújo Filho, Gerardo Maria, Wolf, Peter, Yacubian, Elza Márcia Targas
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anticonvulsants - therapeutic use Brain - drug effects Brain - physiopathology Child Chronosensitivity Circadian Rhythm - physiology Comorbidity Electroencephalography - methods Endophenotypes Female Follow-Up Studies Humans Juvenile myoclonic epilepsy Male Mental Disorders - epidemiology Myoclonic Epilepsy, Juvenile - diagnosis Myoclonic Epilepsy, Juvenile - drug therapy Myoclonic Epilepsy, Juvenile - epidemiology Myoclonic Epilepsy, Juvenile - physiopathology Neurology Praxis induction Prevalence Prognosis Quality of Life Video Recording - methods Young Adult
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Zusammenfassung:	Highlights • There is a male preponderance in juvenile myoclonic epilepsy patients with praxis induction. • Praxis induction is related to focal epileptiform discharges. • Praxis induction is related to loss of the characteristic chronodependency of juvenile myoclonic epilepsy and with reduced response to antiepileptic drugs.
ISSN:	1059-1311 1532-2688
DOI:	10.1016/j.seizure.2015.09.011