Abacavir rechallenge has to be avoided in case of hypersensitivity reaction

Abacavir, an attractive nucleoside analogue may induce a drug-related hypersensitivity in 3% of exposed patients. We report the case of a patient with a lethal drug-related hypersensitivity, underlining the fact that drug re-introduction must be avoided.

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Bibliographische Detailangaben
Veröffentlicht in:	AIDS (London) 1999-07, Vol.13 (11), p.1419-1420
Hauptverfasser:	ESCAUT, L, LIOTIER, J. Y, ALBENGRES, E, CHEMINOT, N, VITTECOQ, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Anaphylaxis - chemically induced Biological and medical sciences Dideoxynucleosides - adverse effects Drug Hypersensitivity - etiology Drug Therapy, Combination Drug toxicity and drugs side effects treatment Fatal Outcome HIV Infections - drug therapy HIV Protease Inhibitors - therapeutic use Human immunodeficiency virus Humans Male Medical sciences Middle Aged Miscellaneous (drug allergy, mutagens, teratogens...) Nelfinavir - therapeutic use Pharmacology. Drug treatments Reverse Transcriptase Inhibitors - adverse effects
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Beschreibung
Zusammenfassung:	Abacavir, an attractive nucleoside analogue may induce a drug-related hypersensitivity in 3% of exposed patients. We report the case of a patient with a lethal drug-related hypersensitivity, underlining the fact that drug re-introduction must be avoided.
ISSN:	0269-9370 1473-5571
DOI:	10.1097/00002030-199907300-00026