Gamma-hydroxybutyrate enhances mood and prosocial behavior without affecting plasma oxytocin and testosterone
Highlights • We investigated putative prosocial, mood altering and neuroendocrine effects of GHB in healthy males. • We found prosocial effects of GHB. • We found mood enhancing effects of GHB. • We found increased progesterone plasma levels after GHB intake. • Oxytocin and testosterone plasma level...
Gespeichert in:
Veröffentlicht in: | Psychoneuroendocrinology 2015-12, Vol.62, p.1-10 |
---|---|
Hauptverfasser: | , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 10 |
---|---|
container_issue | |
container_start_page | 1 |
container_title | Psychoneuroendocrinology |
container_volume | 62 |
creator | Bosch, Oliver G Eisenegger, Christoph Gertsch, Jürg von Rotz, Robin Dornbierer, Dario Gachet, M. Salomé Heinrichs, Markus Wetter, Thomas C Seifritz, Erich Quednow, Boris B |
description | Highlights • We investigated putative prosocial, mood altering and neuroendocrine effects of GHB in healthy males. • We found prosocial effects of GHB. • We found mood enhancing effects of GHB. • We found increased progesterone plasma levels after GHB intake. • Oxytocin and testosterone plasma levels, as well as HPA axis activity remained unaffected after GHB intake. |
doi_str_mv | 10.1016/j.psyneuen.2015.07.167 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1731787833</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S0306453015004011</els_id><sourcerecordid>1731787833</sourcerecordid><originalsourceid>FETCH-LOGICAL-c471t-ef1f77aadd60a5a262a52dd20cd3c7d94858581b1b9a1693d9b6954cb92cf3203</originalsourceid><addsrcrecordid>eNqFkUFv1DAQhS0EokvhL1Q5ckkY24mdXBCogoJUiQNwthx7wnpJ7MV2Cvn3eNmWAxfkgy_vvXnzDSFXFBoKVLw6NMe0eVzRNwxo14BsqJCPyI72ktecC3hMdsBB1G3H4YI8S-kAAKIX7Cm5YILBMDCxI8uNXhZd7zcbw69tXPMWdcYK_V57g6laQrCV9rY6xpCCcXquRtzrOxdi9dPlfVhzpacJTXb-W3WcdVp0VZJy0fo_xowph5QxBo_PyZNJzwlf3P-X5Ov7d1-uP9S3n24-Xr-9rU0raa5xopOUWlsrQHe6tNUds5aBsdxIO7R9Vx4d6ThoKgZuh1EMXWvGgZmJM-CX5OU5t7T-sZYCanHJ4Dxrj2FNikpOZS97zotUnKWmLJgiTuoY3aLjpiioE2p1UA-o1Qm1AqkK6mK8up-xjgvav7YHtkXw5izAsumdw6iScVioWhcLL2WD-_-M1_9EmNl5Z_T8HTdMh7BGXzgqqhJToD6fDn66N-0AWqCU_wbHCKt2</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1731787833</pqid></control><display><type>article</type><title>Gamma-hydroxybutyrate enhances mood and prosocial behavior without affecting plasma oxytocin and testosterone</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Bosch, Oliver G ; Eisenegger, Christoph ; Gertsch, Jürg ; von Rotz, Robin ; Dornbierer, Dario ; Gachet, M. Salomé ; Heinrichs, Markus ; Wetter, Thomas C ; Seifritz, Erich ; Quednow, Boris B</creator><creatorcontrib>Bosch, Oliver G ; Eisenegger, Christoph ; Gertsch, Jürg ; von Rotz, Robin ; Dornbierer, Dario ; Gachet, M. Salomé ; Heinrichs, Markus ; Wetter, Thomas C ; Seifritz, Erich ; Quednow, Boris B</creatorcontrib><description>Highlights • We investigated putative prosocial, mood altering and neuroendocrine effects of GHB in healthy males. • We found prosocial effects of GHB. • We found mood enhancing effects of GHB. • We found increased progesterone plasma levels after GHB intake. • Oxytocin and testosterone plasma levels, as well as HPA axis activity remained unaffected after GHB intake.</description><identifier>ISSN: 0306-4530</identifier><identifier>EISSN: 1873-3360</identifier><identifier>DOI: 10.1016/j.psyneuen.2015.07.167</identifier><identifier>PMID: 26209926</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Adrenocorticotropic Hormone - blood ; Adult ; Affect - drug effects ; Aldosterone - blood ; Altruism ; Brain - drug effects ; Club drug ; Cross-Over Studies ; Dehydroepiandrosterone - blood ; Emotions - drug effects ; Endocrinology & Metabolism ; Fairness ; Gamma-hydroxybutyric acid ; Humans ; Hydrocortisone - blood ; Hydroxybutyrates - pharmacology ; Male ; Oxytocin - blood ; Progesterone - blood ; Psychiatry ; Rape drug ; Social Behavior ; Sodium oxybate ; Testosterone - blood ; Young Adult</subject><ispartof>Psychoneuroendocrinology, 2015-12, Vol.62, p.1-10</ispartof><rights>Elsevier Ltd</rights><rights>2015 Elsevier Ltd</rights><rights>Copyright © 2015 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c471t-ef1f77aadd60a5a262a52dd20cd3c7d94858581b1b9a1693d9b6954cb92cf3203</citedby><cites>FETCH-LOGICAL-c471t-ef1f77aadd60a5a262a52dd20cd3c7d94858581b1b9a1693d9b6954cb92cf3203</cites><orcidid>0000-0002-5807-0859 ; 0000-0003-4087-3650 ; 0000-0001-7933-2865</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.psyneuen.2015.07.167$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26209926$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bosch, Oliver G</creatorcontrib><creatorcontrib>Eisenegger, Christoph</creatorcontrib><creatorcontrib>Gertsch, Jürg</creatorcontrib><creatorcontrib>von Rotz, Robin</creatorcontrib><creatorcontrib>Dornbierer, Dario</creatorcontrib><creatorcontrib>Gachet, M. Salomé</creatorcontrib><creatorcontrib>Heinrichs, Markus</creatorcontrib><creatorcontrib>Wetter, Thomas C</creatorcontrib><creatorcontrib>Seifritz, Erich</creatorcontrib><creatorcontrib>Quednow, Boris B</creatorcontrib><title>Gamma-hydroxybutyrate enhances mood and prosocial behavior without affecting plasma oxytocin and testosterone</title><title>Psychoneuroendocrinology</title><addtitle>Psychoneuroendocrinology</addtitle><description>Highlights • We investigated putative prosocial, mood altering and neuroendocrine effects of GHB in healthy males. • We found prosocial effects of GHB. • We found mood enhancing effects of GHB. • We found increased progesterone plasma levels after GHB intake. • Oxytocin and testosterone plasma levels, as well as HPA axis activity remained unaffected after GHB intake.</description><subject>Adrenocorticotropic Hormone - blood</subject><subject>Adult</subject><subject>Affect - drug effects</subject><subject>Aldosterone - blood</subject><subject>Altruism</subject><subject>Brain - drug effects</subject><subject>Club drug</subject><subject>Cross-Over Studies</subject><subject>Dehydroepiandrosterone - blood</subject><subject>Emotions - drug effects</subject><subject>Endocrinology & Metabolism</subject><subject>Fairness</subject><subject>Gamma-hydroxybutyric acid</subject><subject>Humans</subject><subject>Hydrocortisone - blood</subject><subject>Hydroxybutyrates - pharmacology</subject><subject>Male</subject><subject>Oxytocin - blood</subject><subject>Progesterone - blood</subject><subject>Psychiatry</subject><subject>Rape drug</subject><subject>Social Behavior</subject><subject>Sodium oxybate</subject><subject>Testosterone - blood</subject><subject>Young Adult</subject><issn>0306-4530</issn><issn>1873-3360</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUFv1DAQhS0EokvhL1Q5ckkY24mdXBCogoJUiQNwthx7wnpJ7MV2Cvn3eNmWAxfkgy_vvXnzDSFXFBoKVLw6NMe0eVzRNwxo14BsqJCPyI72ktecC3hMdsBB1G3H4YI8S-kAAKIX7Cm5YILBMDCxI8uNXhZd7zcbw69tXPMWdcYK_V57g6laQrCV9rY6xpCCcXquRtzrOxdi9dPlfVhzpacJTXb-W3WcdVp0VZJy0fo_xowph5QxBo_PyZNJzwlf3P-X5Ov7d1-uP9S3n24-Xr-9rU0raa5xopOUWlsrQHe6tNUds5aBsdxIO7R9Vx4d6ThoKgZuh1EMXWvGgZmJM-CX5OU5t7T-sZYCanHJ4Dxrj2FNikpOZS97zotUnKWmLJgiTuoY3aLjpiioE2p1UA-o1Qm1AqkK6mK8up-xjgvav7YHtkXw5izAsumdw6iScVioWhcLL2WD-_-M1_9EmNl5Z_T8HTdMh7BGXzgqqhJToD6fDn66N-0AWqCU_wbHCKt2</recordid><startdate>20151201</startdate><enddate>20151201</enddate><creator>Bosch, Oliver G</creator><creator>Eisenegger, Christoph</creator><creator>Gertsch, Jürg</creator><creator>von Rotz, Robin</creator><creator>Dornbierer, Dario</creator><creator>Gachet, M. Salomé</creator><creator>Heinrichs, Markus</creator><creator>Wetter, Thomas C</creator><creator>Seifritz, Erich</creator><creator>Quednow, Boris B</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-5807-0859</orcidid><orcidid>https://orcid.org/0000-0003-4087-3650</orcidid><orcidid>https://orcid.org/0000-0001-7933-2865</orcidid></search><sort><creationdate>20151201</creationdate><title>Gamma-hydroxybutyrate enhances mood and prosocial behavior without affecting plasma oxytocin and testosterone</title><author>Bosch, Oliver G ; Eisenegger, Christoph ; Gertsch, Jürg ; von Rotz, Robin ; Dornbierer, Dario ; Gachet, M. Salomé ; Heinrichs, Markus ; Wetter, Thomas C ; Seifritz, Erich ; Quednow, Boris B</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c471t-ef1f77aadd60a5a262a52dd20cd3c7d94858581b1b9a1693d9b6954cb92cf3203</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adrenocorticotropic Hormone - blood</topic><topic>Adult</topic><topic>Affect - drug effects</topic><topic>Aldosterone - blood</topic><topic>Altruism</topic><topic>Brain - drug effects</topic><topic>Club drug</topic><topic>Cross-Over Studies</topic><topic>Dehydroepiandrosterone - blood</topic><topic>Emotions - drug effects</topic><topic>Endocrinology & Metabolism</topic><topic>Fairness</topic><topic>Gamma-hydroxybutyric acid</topic><topic>Humans</topic><topic>Hydrocortisone - blood</topic><topic>Hydroxybutyrates - pharmacology</topic><topic>Male</topic><topic>Oxytocin - blood</topic><topic>Progesterone - blood</topic><topic>Psychiatry</topic><topic>Rape drug</topic><topic>Social Behavior</topic><topic>Sodium oxybate</topic><topic>Testosterone - blood</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bosch, Oliver G</creatorcontrib><creatorcontrib>Eisenegger, Christoph</creatorcontrib><creatorcontrib>Gertsch, Jürg</creatorcontrib><creatorcontrib>von Rotz, Robin</creatorcontrib><creatorcontrib>Dornbierer, Dario</creatorcontrib><creatorcontrib>Gachet, M. Salomé</creatorcontrib><creatorcontrib>Heinrichs, Markus</creatorcontrib><creatorcontrib>Wetter, Thomas C</creatorcontrib><creatorcontrib>Seifritz, Erich</creatorcontrib><creatorcontrib>Quednow, Boris B</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Psychoneuroendocrinology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bosch, Oliver G</au><au>Eisenegger, Christoph</au><au>Gertsch, Jürg</au><au>von Rotz, Robin</au><au>Dornbierer, Dario</au><au>Gachet, M. Salomé</au><au>Heinrichs, Markus</au><au>Wetter, Thomas C</au><au>Seifritz, Erich</au><au>Quednow, Boris B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Gamma-hydroxybutyrate enhances mood and prosocial behavior without affecting plasma oxytocin and testosterone</atitle><jtitle>Psychoneuroendocrinology</jtitle><addtitle>Psychoneuroendocrinology</addtitle><date>2015-12-01</date><risdate>2015</risdate><volume>62</volume><spage>1</spage><epage>10</epage><pages>1-10</pages><issn>0306-4530</issn><eissn>1873-3360</eissn><abstract>Highlights • We investigated putative prosocial, mood altering and neuroendocrine effects of GHB in healthy males. • We found prosocial effects of GHB. • We found mood enhancing effects of GHB. • We found increased progesterone plasma levels after GHB intake. • Oxytocin and testosterone plasma levels, as well as HPA axis activity remained unaffected after GHB intake.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>26209926</pmid><doi>10.1016/j.psyneuen.2015.07.167</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0002-5807-0859</orcidid><orcidid>https://orcid.org/0000-0003-4087-3650</orcidid><orcidid>https://orcid.org/0000-0001-7933-2865</orcidid><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0306-4530 |
ispartof | Psychoneuroendocrinology, 2015-12, Vol.62, p.1-10 |
issn | 0306-4530 1873-3360 |
language | eng |
recordid | cdi_proquest_miscellaneous_1731787833 |
source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
subjects | Adrenocorticotropic Hormone - blood Adult Affect - drug effects Aldosterone - blood Altruism Brain - drug effects Club drug Cross-Over Studies Dehydroepiandrosterone - blood Emotions - drug effects Endocrinology & Metabolism Fairness Gamma-hydroxybutyric acid Humans Hydrocortisone - blood Hydroxybutyrates - pharmacology Male Oxytocin - blood Progesterone - blood Psychiatry Rape drug Social Behavior Sodium oxybate Testosterone - blood Young Adult |
title | Gamma-hydroxybutyrate enhances mood and prosocial behavior without affecting plasma oxytocin and testosterone |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T04%3A58%3A24IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Gamma-hydroxybutyrate%20enhances%20mood%20and%20prosocial%20behavior%20without%20affecting%20plasma%20oxytocin%20and%20testosterone&rft.jtitle=Psychoneuroendocrinology&rft.au=Bosch,%20Oliver%20G&rft.date=2015-12-01&rft.volume=62&rft.spage=1&rft.epage=10&rft.pages=1-10&rft.issn=0306-4530&rft.eissn=1873-3360&rft_id=info:doi/10.1016/j.psyneuen.2015.07.167&rft_dat=%3Cproquest_cross%3E1731787833%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1731787833&rft_id=info:pmid/26209926&rft_els_id=1_s2_0_S0306453015004011&rfr_iscdi=true |