Contactin-5 expression during development and wiring of the thalamocortical system

Highlights • Cntn5 is highly expressed in glutamatergic nuclei of the dorsal thalamus. • Cntn5 is developmentally expressed from E15.5 onward and extends in adulthood at lower levels. • The cerebral cortex contains Cntn5-expressing neurons in cortical layer Va.

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Bibliographische Detailangaben
Veröffentlicht in:	Neuroscience 2015-12, Vol.310, p.106-113
Hauptverfasser:	Kleijer, K.T.E, Zuko, A, Shimoda, Y, Watanabe, K, Burbach, J.P.H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn autism spectrum disorder beta-Galactosidase - genetics beta-Galactosidase - metabolism Carrier Proteins - genetics Carrier Proteins - metabolism Cell Cycle Proteins - genetics Cell Cycle Proteins - metabolism Cerebral Cortex - embryology Cerebral Cortex - growth & development Cerebral Cortex - metabolism Complex Mixtures - metabolism contactin-5 Contactins - genetics Contactins - metabolism development Embryo, Mammalian Gene Expression Regulation, Developmental - genetics Mice Mice, Transgenic Neural Pathways - physiology Neurology Neurons - metabolism thalamocortical circuit thalamus Thalamus - embryology Thalamus - growth & development Thalamus - metabolism Transcription Factors - metabolism Vesicular Glutamate Transport Protein 2 - metabolism
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Beschreibung
Zusammenfassung:	Highlights • Cntn5 is highly expressed in glutamatergic nuclei of the dorsal thalamus. • Cntn5 is developmentally expressed from E15.5 onward and extends in adulthood at lower levels. • The cerebral cortex contains Cntn5-expressing neurons in cortical layer Va.
ISSN:	0306-4522 1873-7544
DOI:	10.1016/j.neuroscience.2015.09.039