A novel FRET-based ratiometric fluorescent probe for highly sensitive detection of hydrogen sulfide

A novel FRET-based ratiometric fluorescent probe for highly sensitive detection of hydrogen sulfide

A novel FRET-based ratiometric fluorescent probe H2S-CR for the quantitative detection of H 2 S was designed and synthesized. It exhibits a response time of 20 min, a considerable fluorescence signal enhancement (15 fold), and an extremely low detection limit (19 nM). It can be successfully applied...

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Veröffentlicht in:RSC advances 2015-01, Vol.5 (23), p.17797-17801
Hauptverfasser: Huang, Kunzhu, Yu, Lun, Xu, Pengfei, Zhang, Xintong, Zeng, Wenbin
Format: Artikel
Sprache:eng
Schlagworte:
Fluorescence
Fretting
Hydrogen sulfide
Imaging
Response time
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Zusammenfassung:A novel FRET-based ratiometric fluorescent probe H2S-CR for the quantitative detection of H 2 S was designed and synthesized. It exhibits a response time of 20 min, a considerable fluorescence signal enhancement (15 fold), and an extremely low detection limit (19 nM). It can be successfully applied to imaging H 2 S in living cells.
ISSN:2046-2069
2046-2069
DOI:10.1039/C4RA16578K