A concise synthetic approach toward tamiflu (oseltamivir phosphate): cis-aziridine as the key synthon and RCM

The key synthon cis -aziridine has been efficiently utilised for the synthesis of oseltamivir phosphate, using Wittig olefination, Barbier addition, Mitsunobu reaction and ring closing metathesis (RCM) as key essentials.

Bibliographische Detailangaben

Veröffentlicht in:	RSC advances 2014-01, Vol.4 (22), p.11417-11419
Hauptverfasser:	Chavan, Subhash P., Chavan, Prakash N., Khairnar, Lalit B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Decomposition reactions Metathesis Phosphates RCM Synthesis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!