Finding of thiosulfate pathway for synthesis of organic sulfur compounds in Saccharomyces cerevisiae and improvement of ethanol production

We found that Saccharomyces cerevisiae utilizes thiosulfate as a sole sulfur source. The energetically-favored thiosulfate rather than sulfate as sulfur sources is also more effective for improving growth and ethanol-production rate in S. cerevisiae due to high levels of intracellular NADPH during t...

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Veröffentlicht in:	Journal of bioscience and bioengineering 2015-12, Vol.120 (6), p.666-669
Hauptverfasser:	Funahashi, Eri, Saiki, Kyohei, Honda, Kurara, Sugiura, Yuki, Kawano, Yusuke, Ohtsu, Iwao, Watanabe, Daisuke, Wakabayashi, Yukari, Abe, Tetsuya, Nakanishi, Tsuyoshi, Suematsu, Makoto, Takagi, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Ethanol - analysis Ethanol - metabolism Ethanol production NADP - metabolism Pentose phoshate pathway Saccharomyces cerevisiae Saccharomyces cerevisiae - chemistry Saccharomyces cerevisiae - growth & development Saccharomyces cerevisiae - metabolism Sulfur metabolism Sulfur metabolome Thiosulfate assimilation Thiosulfates - metabolism
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Zusammenfassung:	We found that Saccharomyces cerevisiae utilizes thiosulfate as a sole sulfur source. The energetically-favored thiosulfate rather than sulfate as sulfur sources is also more effective for improving growth and ethanol-production rate in S. cerevisiae due to high levels of intracellular NADPH during thiosulfate utilization.
ISSN:	1389-1723 1347-4421
DOI:	10.1016/j.jbiosc.2015.04.011