Randomized, double-blinded, vehicle-controlled, split-face study to evaluate the effects of topical application of a Gold Silk Sericin/Niacinamide/Signaline complex on biophysical parameters related to skin ageing

Synopsis Objective To investigate the effects of topical application of a Gold Silk Sericin (GSS) complex on biophysical parameters related to skin ageing. Methods A range of non‐invasive bioengineering methods were deployed in an 8‐week randomized, double‐blinded, vehicle‐controlled, split‐face study among 40 female subjects aged 40–70. Endpoints measured included expert grades of skin condition, stratum corneum (SC) hydration, SC barrier function, elasticity and surface topography. Results The GSS complex produced significant single‐variable (P