Treatment of climacteric symptoms in survivors of gynaecological cancer

Highlights • Physicians are reluctant in prescribing HRTin gynaecological cancer survivors because of the fear that hormones may influence the risk of recurrence. • No evidence of increased risk in the available studies on HRT in survivors of endometrial, ovarian and squamous cervical cancer, even if no definitive results have been formulated. • The positive effect of HRT on the quality of life seems to outweigh the unfounded suspicion about an increased risk of recurrence. • It is mandatory to inform patients about alternative therapies other than estrogens, in particular for prevention of osteoporosis and cardiovascular disease.