Isolation and culture of human oligodendrocyte precursor cells from neurospheres

Highlights • We developed a reproducible, simple, and economical method of obtaining human OPCs from neurospheres. • Isolated human OPCs have high purity and robust proliferative capacity. • After induction, the OPCs can differentiate into oligodendrocytes.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Brain research bulletin 2015-09, Vol.118, p.17-24
Hauptverfasser:	Lu, Yabin, Yang, Yinxiang, Wang, Zhaoyan, Wang, Caiying, Du, Qingan, Wang, Qian, Luan, Zuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Aborted Fetus - cytology Brain - cytology Cell Culture Techniques - methods Cell Differentiation - physiology Differentiation Humans Neural Stem Cells - cytology Neurology Neurosphere Oligodendrocyte Oligodendrocyte precursor cells Oligodendroglia - cytology Proliferation Tissue Culture Techniques - methods
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights • We developed a reproducible, simple, and economical method of obtaining human OPCs from neurospheres. • Isolated human OPCs have high purity and robust proliferative capacity. • After induction, the OPCs can differentiate into oligodendrocytes.
ISSN:	0361-9230 1873-2747
DOI:	10.1016/j.brainresbull.2015.08.008