Alternative mRNA transcription, processing, and translation: insights from RNA sequencing
Highlights • RNA sequencing uncovers mechanisms regulating gene expression. • Use of alternative TSSs, PASs, and exons is the rule. • Alternative translation initiation at 5′-UTRs and downstream codons is widespread. • Transcription, RNA processing, and translation are often interdependent processes...
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| Veröffentlicht in: | Trends in genetics 2015-03, Vol.31 (3), p.128-139 |
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| container_title | Trends in genetics |
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| creator | de Klerk, Eleonora t Hoen, Peter A.C |
| description | Highlights • RNA sequencing uncovers mechanisms regulating gene expression. • Use of alternative TSSs, PASs, and exons is the rule. • Alternative translation initiation at 5′-UTRs and downstream codons is widespread. • Transcription, RNA processing, and translation are often interdependent processes. |
| doi_str_mv | 10.1016/j.tig.2015.01.001 |
| format | Article |
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| ispartof | Trends in genetics, 2015-03, Vol.31 (3), p.128-139 |
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| language | eng |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | alternative polyadenylation Alternative Splicing gene expression Gene Expression Profiling High-Throughput Nucleotide Sequencing - methods Humans Medical Education Polyadenylation Promoter Regions, Genetic - genetics Protein Biosynthesis RNA sequencing RNA, Messenger - genetics Sequence Analysis, RNA Transcription, Genetic Transcriptome translation |
| title | Alternative mRNA transcription, processing, and translation: insights from RNA sequencing |
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