Calnexin is a novel sero-diagnostic marker for lung cancer

Highlights • Monoclonal antibody for CANX protein was established by the random immunization method. • Serum levels of CANX protein in lung cancer patients were detected by the RPPA method. • CANX protein is a useful early sero-diagnostic marker for lung cancer.

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Bibliographische Detailangaben
Veröffentlicht in:	Lung cancer (Amsterdam, Netherlands) Netherlands), 2015-11, Vol.90 (2), p.342-345
Hauptverfasser:	Kobayashi, Makoto, Nagashio, Ryo, Jiang, Shi-Xu, Saito, Keita, Tsuchiya, Benio, Ryuge, Shinichiro, Katono, Ken, Nakashima, Hiroyasu, Fukuda, Eriko, Goshima, Naoki, Satoh, Yukitoshi, Masuda, Noriyuki, Saegusa, Makoto, Sato, Yuichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - diagnosis Adenocarcinoma - immunology Adenocarcinoma of Lung Aged Antibodies, Monoclonal - immunology Antibody-based proteomics Antigens, Neoplasm - immunology Biomarkers, Tumor - immunology Calnexin Calnexin - immunology Cell Line, Tumor Female Hematology, Oncology and Palliative Medicine Humans Lung cancer Lung Neoplasms - diagnosis Lung Neoplasms - immunology Male Protein Array Analysis - methods Pulmonary/Respiratory Sero-diagnostic marker
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Beschreibung
Zusammenfassung:	Highlights • Monoclonal antibody for CANX protein was established by the random immunization method. • Serum levels of CANX protein in lung cancer patients were detected by the RPPA method. • CANX protein is a useful early sero-diagnostic marker for lung cancer.
ISSN:	0169-5002 1872-8332
DOI:	10.1016/j.lungcan.2015.08.015