Synthesis and insecticidal activity of CGA 293 theta 343 - a novel broad-spectrum insecticide

CGA 293 theta 343 is a novel broad-spectrum insecticide currently under world-wide development by Novartis Crop Protection. CGA 293 theta 343 belongs to a new class of highly active compounds - the neonicotinoids - and provides excellent control of a wide variety of commercially important pests. It possesses contact, stomach and systemic activity. The long-lasting residual effect is a special benefit of this compound. In general, CGA 293 theta 343 shows biological activity in the laboratory equal to or better than the neonicotinoids so far introduced to the market. Synthetic aspects, structure-activity relationships and the biological profile are discussed.