The insecticidal activity of derivatives of the ionophore X-206

The insecticidal activity of derivatives of the ionophore X-206

The naturally‐occurring ionophore X206, originally isolated for its antibacterial activity, also exhibits broad insecticidal and acaricidal activity. This summary reports structure/activity studies with X206 and 34 derivatives as well as mode of action studies. Although many compounds showed promisi...

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Veröffentlicht in:Pesticide Science 1999-03, Vol.55 (3), p.379-381
Hauptverfasser: Fiebich, Katrin, Hoermann, Aldo, Mutz, Michael, O'Sullivan, Anthony C, Rindlisbacher, Alfred, Struber, Fritz
Format: Artikel
Sprache:eng
Schlagworte:
acaracide
insecticide
ionophore
mode of action
X206 derivatives
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Beschreibung
Zusammenfassung:The naturally‐occurring ionophore X206, originally isolated for its antibacterial activity, also exhibits broad insecticidal and acaricidal activity. This summary reports structure/activity studies with X206 and 34 derivatives as well as mode of action studies. Although many compounds showed promising insecticidal activity, it was only of a contact activity nature; furthermore, the acute LD50 of the compounds in rats precluded further development of these compounds. © 1999 Society of Chemical Industry
ISSN:0031-613X
1526-498X
1096-9063
DOI:10.1002/(SICI)1096-9063(199903)55:3<379::AID-PS919>3.0.CO;2-M