Radiotherapy after mastectomy for screen-detected ductal carcinoma in situ

Abstract Background A role for radiotherapy after mastectomy for ductal carcinoma in situ (DCIS) is unclear. Using a prospective audit of DCIS detected through the NHS Breast Screening Programme we sought to determine a rationale for the use of post mastectomy radiotherapy for DCIS. Methods Over a n...

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Veröffentlicht in:	European journal of surgical oncology 2015-10, Vol.41 (10), p.1406-1410
Hauptverfasser:	Clements, K, Dodwell, D, Lawrence, G, Ball, G, Francis, A, Pinder, S, Sawyer, E, Wallis, M, Thompson, A.M
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Breast cancer Breast Neoplasms - diagnosis Breast Neoplasms - radiotherapy Breast Neoplasms - surgery Carcinoma, Intraductal, Noninfiltrating - diagnosis Carcinoma, Intraductal, Noninfiltrating - radiotherapy Carcinoma, Intraductal, Noninfiltrating - surgery Cohort Studies DCIS Disease-Free Survival Early Detection of Cancer Female Hematology, Oncology and Palliative Medicine Humans Mastectomy Middle Aged Neoplasm Recurrence, Local Neoplasm, Residual Prospective Studies Radiotherapy Radiotherapy, Adjuvant - methods Sloane project Surgery
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Zusammenfassung:	Abstract Background A role for radiotherapy after mastectomy for ductal carcinoma in situ (DCIS) is unclear. Using a prospective audit of DCIS detected through the NHS Breast Screening Programme we sought to determine a rationale for the use of post mastectomy radiotherapy for DCIS. Methods Over a nine year period, from 9972 patients with screen-detected DCIS and complete surgical, pathology, radiotherapy and follow up data, 2944 women underwent mastectomy for DCIS of whom 33 (1.1%) received radiotherapy. Results Use of post mastectomy radiotherapy was significantly associated with a close (
ISSN:	0748-7983 1532-2157
DOI:	10.1016/j.ejso.2015.07.021