Virological analysis of inherited chromosomally integrated human herpesvirus‐6 in three hematopoietic stem cell transplant patients

We analyzed 3 hematopoietic stem cell transplant (HSCT) recipients with inherited chromosomally integrated human herpesvirus‐6 (inherited CIHHV‐6). Cases 1 (inherited CIHHV‐6A) and 2 (inherited CIHHV‐6B) were inherited CIHHV‐6 recipients. Case 3 received bone marrow from a donor with inherited CIHHV...

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Veröffentlicht in:Transplant infectious disease 2015-10, Vol.17 (5), p.728-731
Hauptverfasser: Miura, H., Kawamura, Y., Kudo, K., Ihira, M., Ohye, T., Kurahashi, H., Kawashima, N., Miyamura, K., Yoshida, N., Kato, K., Takahashi, Y., Kojima, S., Yoshikawa, T.
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container_end_page 731
container_issue 5
container_start_page 728
container_title Transplant infectious disease
container_volume 17
creator Miura, H.
Kawamura, Y.
Kudo, K.
Ihira, M.
Ohye, T.
Kurahashi, H.
Kawashima, N.
Miyamura, K.
Yoshida, N.
Kato, K.
Takahashi, Y.
Kojima, S.
Yoshikawa, T.
description We analyzed 3 hematopoietic stem cell transplant (HSCT) recipients with inherited chromosomally integrated human herpesvirus‐6 (inherited CIHHV‐6). Cases 1 (inherited CIHHV‐6A) and 2 (inherited CIHHV‐6B) were inherited CIHHV‐6 recipients. Case 3 received bone marrow from a donor with inherited CIHHV‐6B. Following HSCT, HHV‐6B was isolated from Case 1. HHV‐6A and ‐6B messenger RNAs were detected in Cases 1 and 3.
doi_str_mv 10.1111/tid.12419
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HHV‐6A and ‐6B messenger RNAs were detected in Cases 1 and 3.</description><subject>Bone marrow</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>DNA, Viral - isolation &amp; purification</subject><subject>Female</subject><subject>Hematopoietic Stem Cell Transplantation</subject><subject>Herpesvirus 6, Human - genetics</subject><subject>Herpesvirus 6, Human - isolation &amp; purification</subject><subject>HSCT</subject><subject>Humans</subject><subject>inherited CIHHV‐6</subject><subject>Male</subject><subject>reactivation</subject><subject>RT‐PCR</subject><subject>Stem cells</subject><subject>Transplants &amp; implants</subject><subject>Virus Integration</subject><subject>Young Adult</subject><issn>1398-2273</issn><issn>1399-3062</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10btKBDEUBuAgivfCF5CAjRajk8w1pXgHwWa1Hc5mzriRzGRMMsp2NvY-o09ixl0tBNMk5Hz8hPyE7LH4mIV14lV9zHjKxArZZIkQURLnfPX7XEacF8kG2XLuKY5ZIVKxTjZ4zoo8y_kmeX9Q1mjzqCRoCh3ouVOOmoaqboZWeaypnFnTGmda0Hoe7j0-WhgHs6GFjgbWo3tRdnCfbx95ANTPLGIYtOBNbxR6Janz2FKJWlNvoXO9hs7THrzCzrsdstaAdri73LfJ_eXF5Ow6ur27ujk7vY1kyhMRNUKUQjJIsagziVMoBIdpk0wFlw3UZcrLLGY15whMNBIlr1EWZcYYBlHLZJscLnJ7a54HdL5qlRsfBR2awVWs4HGaijLNAj34Q5_MYMMHjYqJpMyyZFRHCyWtcc5iU_VWtWDnFYursZsqdFN9dxPs_jJxmLZY_8qfMgI4WYBXpXH-f1I1uTlfRH4B7LadgQ</recordid><startdate>201510</startdate><enddate>201510</enddate><creator>Miura, H.</creator><creator>Kawamura, Y.</creator><creator>Kudo, K.</creator><creator>Ihira, M.</creator><creator>Ohye, T.</creator><creator>Kurahashi, H.</creator><creator>Kawashima, N.</creator><creator>Miyamura, K.</creator><creator>Yoshida, N.</creator><creator>Kato, K.</creator><creator>Takahashi, Y.</creator><creator>Kojima, S.</creator><creator>Yoshikawa, T.</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7U9</scope><scope>8FD</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>201510</creationdate><title>Virological analysis of inherited chromosomally integrated human herpesvirus‐6 in three hematopoietic stem cell transplant patients</title><author>Miura, H. ; 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subjects Bone marrow
Child
Child, Preschool
DNA, Viral - isolation & purification
Female
Hematopoietic Stem Cell Transplantation
Herpesvirus 6, Human - genetics
Herpesvirus 6, Human - isolation & purification
HSCT
Humans
inherited CIHHV‐6
Male
reactivation
RT‐PCR
Stem cells
Transplants & implants
Virus Integration
Young Adult
title Virological analysis of inherited chromosomally integrated human herpesvirus‐6 in three hematopoietic stem cell transplant patients
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