Virological analysis of inherited chromosomally integrated human herpesvirus‐6 in three hematopoietic stem cell transplant patients

Virological analysis of inherited chromosomally integrated human herpesvirus‐6 in three hematopoietic stem cell transplant patients

We analyzed 3 hematopoietic stem cell transplant (HSCT) recipients with inherited chromosomally integrated human herpesvirus‐6 (inherited CIHHV‐6). Cases 1 (inherited CIHHV‐6A) and 2 (inherited CIHHV‐6B) were inherited CIHHV‐6 recipients. Case 3 received bone marrow from a donor with inherited CIHHV...

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Veröffentlicht in:Transplant infectious disease 2015-10, Vol.17 (5), p.728-731
Hauptverfasser: Miura, H., Kawamura, Y., Kudo, K., Ihira, M., Ohye, T., Kurahashi, H., Kawashima, N., Miyamura, K., Yoshida, N., Kato, K., Takahashi, Y., Kojima, S., Yoshikawa, T.
Format: Artikel
Sprache:eng
Schlagworte:
Bone marrow
Child
Child, Preschool
DNA, Viral - isolation & purification
Female
Hematopoietic Stem Cell Transplantation
Herpesvirus 6, Human - genetics
Herpesvirus 6, Human - isolation & purification
HSCT
Humans
inherited CIHHV‐6
Male
reactivation
RT‐PCR
Stem cells
Transplants & implants
Virus Integration
Young Adult
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Zusammenfassung:We analyzed 3 hematopoietic stem cell transplant (HSCT) recipients with inherited chromosomally integrated human herpesvirus‐6 (inherited CIHHV‐6). Cases 1 (inherited CIHHV‐6A) and 2 (inherited CIHHV‐6B) were inherited CIHHV‐6 recipients. Case 3 received bone marrow from a donor with inherited CIHHV‐6B. Following HSCT, HHV‐6B was isolated from Case 1. HHV‐6A and ‐6B messenger RNAs were detected in Cases 1 and 3.
ISSN:1398-2273
1399-3062
DOI:10.1111/tid.12419