Thermoregulatory And Cardiovascular Responses To Creatine, Glycerol And Alpha Lipoic Acid In Trained Cyclists

To determine whether Cr/Gly-induced thermoregulatory and cardiovascular responses are maintained or even enhanced when the majority (~75%) of the Glu in the Cr/Gly supplement is replaced with the insulintropic agent alpha lipoic acid (Ala). 22 healthy endurance trained cyclists were randomly assigne...

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Veröffentlicht in:Medicine and science in sports and exercise 2012-05, Vol.44 (5S), p.604-604
Hauptverfasser: Polyviou, Thelma P, Pantazis, Takas, Lee, Wu Chean, Malkova, Dalia, Pitsiladis, Yannis P
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Sprache:eng
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Zusammenfassung:To determine whether Cr/Gly-induced thermoregulatory and cardiovascular responses are maintained or even enhanced when the majority (~75%) of the Glu in the Cr/Gly supplement is replaced with the insulintropic agent alpha lipoic acid (Ala). 22 healthy endurance trained cyclists were randomly assigned to receive either 11.4 g of Cr-H sub(2)O, 1 g of Gly/kg body mass (BM) and 150 g of Glu (Cr/Gly/Glu) or 11.4 g of Cr- H sub(2)O, 1 g of Gly/kg BM, 100 g of Glu and 1000 mg Ala (Cr/Gly/Glu/Ala) for 7 days. Exercise trials were conducted pre- and post-supplementation and involved 40 min of constant-load cycling exercise at 70% VO2max followed by a self-paced 16.1 km time trial at 30 [degrees]C and 70% relative humidity. BM increase, although not statistically significant (p=0.056), was noted in most individuals: 1.75(0.1-3.0) kg and 0.9(0.0-2.1) kg (median (range) in the Cr/Gly/Glu and in the Cr/Gly/Glu/Ala, respectively.
ISSN:0195-9131